Il17rc - interleukin 17 receptor C Gene

Also Known as Il17rl; Gm19850; IL-17RC; IL17-RC; IL17-RL; 1110025H02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 171095

Summary

Enables signaling receptor binding activity. Involved in defense response to fungus; granulocyte chemotaxis; and positive regulation of interleukin-6 production. Acts upstream of or within positive regulation of cytokine production involved in inflammatory response. Located in cell surface and plasma membrane. Is expressed in hip; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis. Orthologous to human IL17RC (interleukin 17 receptor C). [provided by Alliance of Genome Resources, Apr 2022]

Il17rc Products (2)

mRNA Protein Name
NM_134159.4 NP_598920.3 interleukin-17 receptor C isoform 2 precursor
NM_178942.1 NP_849273.1 interleukin-17 receptor C isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20554964 MGI
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
20554964 MGI
Biological Process GO Annotation Evidence References Source
involved in defense response to fungus IMP
IMP: Inferred from mutant phenotype
20554964 MGI
involved in granulocyte chemotaxis IMP
IMP: Inferred from mutant phenotype
20554964 MGI
acts upstream of or within positive regulation of cytokine production involved in inflammatory response IGI
IGI: Inferred from genetic interaction
16785495 MGI
involved in positive regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
20554964 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
20554964 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17911633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-17 receptor C

  • IL-17 receptor C

  • IL-17RL

  • interleukin-17 receptor-like protein

  • zcytoR14

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06704 IL17RC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21141 Il17rc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27658 Il17rc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il17rc NCBI NCBI:84818