Chrnb3 - cholinergic receptor nicotinic beta 3 subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171131

Summary

Enables acetylcholine binding activity. Contributes to heterocyclic compound binding activity. Predicted to be involved in several processes, including cholinergic synaptic transmission; regulation of synaptic vesicle exocytosis; and response to nicotine. Located in membrane and neuron projection. Part of acetylcholine-gated channel complex. Orthologous to human CHRNB3 (cholinergic receptor nicotinic beta 3 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrnb3 Products (1)

mRNA Protein Name
NM_133597.2 NP_598281.1 neuronal acetylcholine receptor subunit beta-3 precursor
Molecular Function GO Annotation Evidence References Source
enables acetylcholine binding IDA
IDA: Inferred from direct assay
9030613 RGD
contributes to heterocyclic compound binding IPI
IPI: Inferred from physical interaction
16129735 RGD
Cellular Component GO Annotation Evidence References Source
part of acetylcholine-gated channel complex IDA
IDA: Inferred from direct assay
9030613 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
16129735 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal acetylcholine receptor subunit beta-3

  • cholinergic receptor, nicotinic beta 3

  • cholinergic receptor, nicotinic, beta 3 (neuronal)

  • cholinergic receptor, nicotinic, beta polypeptide 3

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrnb3 NCBI NCBI:1142