Syt12 - synaptotagmin XII Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 171180

Summary

Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in long-term synaptic potentiation. Colocalizes with hippocampal mossy fiber to CA3 synapse and synaptic vesicle. Is expressed in adrenal gland and ventral grey horn. Orthologous to human SYT12 (synaptotagmin 12). [provided by Alliance of Genome Resources, Apr 2022]

Syt12 Products (1)

mRNA Protein Name
NM_134164.5 NP_598925.1 synaptotagmin-12

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
23739973 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
23739973 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
23739973 MGI
Cellular Component GO Annotation Evidence References Source
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
23739973 MGI
colocalizes with hippocampal mossy fiber to CA3 synapse IMP
IMP: Inferred from mutant phenotype
23739973 MGI
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: Inferred from mutant phenotype
23739973 MGI
colocalizes with synaptic vesicle IDA
IDA: Inferred from direct assay
17190793 MGI
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
17190793 MGI
is active in synaptic vesicle membrane IMP
IMP: Inferred from mutant phenotype
17190793 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptotagmin-12

  • sytXII

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14108 SYT11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14109 SYT12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syt12 NCBI NCBI:91683