Mxd3 - Max dimerization protein 3 Gene

Also Known as Mad3; bHLHc13; 4631412E13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17121

Summary

Contributes to DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of transcription, DNA-templated. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including central nervous system; genitourinary system; limb mesenchyme; retina; and thymus. Orthologous to human MXD3 (MAX dimerization protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Mxd3 Products (1)

mRNA Protein Name
NM_016662.5 NP_057871.2 max dimerization protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to DNA binding IDA
IDA: Inferred from direct assay
8521822 MGI
contributes to DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
8521822 MGI
contributes to DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
8521822 MGI
contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
8521822 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8521822 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of DNA-templated transcription IGI
IGI: Inferred from genetic interaction
8521822 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8521822 MGI
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase II transcription regulator complex IMP
IMP: Inferred from mutant phenotype
8521822 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

max dimerization protein 3

  • max dimerizer 3

  • max-associated protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08862 MXD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mxd3 NCBI NCBI:83463