Mxd4 - Max dimerization protein 4 Gene

Also Known as Mad4; bHLHc12; 2810410A03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17122

Summary

Contributes to DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of transcription, DNA-templated. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including craniocervical region bone; limb mesenchyme; neural tube; skin; and thymus. Orthologous to human MXD4 (MAX dimerization protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Mxd4 Products (1)

mRNA Protein Name
NM_010753.3 NP_034883.2 max dimerization protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to DNA binding IDA
IDA: Inferred from direct assay
8521822 MGI
contributes to DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
8521822 MGI
contributes to DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
8521822 MGI
contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
8521822 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8521822 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of DNA-templated transcription IGI
IGI: Inferred from genetic interaction
8521822 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8521822 MGI
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase II transcription regulator complex IMP
IMP: Inferred from mutant phenotype
8521822 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

max dimerization protein 4

  • max dimerizer 4

  • max-associated protein 4

  • max-interacting transcriptional repressor MAD4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08863 MXD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mxd4 NCBI NCBI:10608