Matn2 - matrilin 2 Gene

Also Known as Crtm2; matrilin-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17181

Summary

Predicted to enable calcium ion binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within neurogenesis and response to axon injury. Located in basement membrane. Is expressed in several structures, including brain; chondrocranium; forelimb; heart; and spinal cord meninges. Orthologous to human MATN2 (matrilin 2). [provided by Alliance of Genome Resources, Apr 2022]

Matn2 Products (2)

mRNA Protein Name
NM_001358780.1 NP_001345709.1 matrilin-2 isoform 1 precursor
NM_016762.2 NP_058042.2 matrilin-2 isoform 2 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon guidance IGI
IGI: Inferred from genetic interaction
19295126 MGI
acts upstream of or within dendrite regeneration IMP
IMP: Inferred from mutant phenotype
19295126 MGI
acts upstream of or within glial cell migration IDA
IDA: Inferred from direct assay
19295126 MGI
acts upstream of or within neuron migration IDA
IDA: Inferred from direct assay
19295126 MGI
acts upstream of or within neuron projection development IDA
IDA: Inferred from direct assay
19295126 MGI
acts upstream of or within response to axon injury IMP
IMP: Inferred from mutant phenotype
19295126 MGI
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
19295126 MGI
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
10224097 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
11102754 MGI
part of matrilin complex IPI
IPI: Inferred from physical interaction
10224097 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

matrilin-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08171 MATN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Matn2 NCBI NCBI:4147