2. Gene
  3. Mns1 - meiosis-specific nuclear structural protein 1 Gene

Mns1 - meiosis-specific nuclear structural protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 17427 | Gene type: protein coding

About Mns1

Summary

Predicted to enable identical protein binding activity. Involved in positive regulation of cilium assembly and sperm axoneme assembly. Acts upstream of or within cilium organization and left/right axis specification. Located in cytoskeleton; nuclear envelope; and sperm flagellum. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in visceral heterotaxy. Orthologous to human MNS1 (meiosis specific nuclear structural 1). [provided by Alliance of Genome Resources, Apr 2022]

Mns1 Products(3)

mRNA Protein Name
NM_001410429.1 NP_001397358.1 meiosis-specific nuclear structural protein 1 isoform 2
NM_001410430.1 NP_001397359.1 meiosis-specific nuclear structural protein 1 isoform 3
NM_008613.4 NP_032639.1 meiosis-specific nuclear structural protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
37198331 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cilium organization IMP
IMP: Inferred from mutant phenotype
22396656 MGI
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
37295417 MGI
acts upstream of or within left/right axis specification IMP
IMP: Inferred from mutant phenotype
22396656 MGI
involved in positive regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
22396656 MGI
involved in sperm axoneme assembly IMP
IMP: Inferred from mutant phenotype
22396656 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
22396656 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in axonemal A tubule inner sheath IDA
IDA: Inferred from direct assay
37295417 MGI
located in axoneme IDA
IDA: Inferred from direct assay
22396656 MGI
located in intermediate filament IDA
IDA: Inferred from direct assay
8032679 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
8032679 MGI
is active in sperm flagellum IDA
IDA: Inferred from direct assay
37295417 MGI
located in sperm flagellum IDA
IDA: Inferred from direct assay
22396656 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

meiosis-specific nuclear structural protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08569 MNS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mns1 NCBI NCBI:55329