Map7 - microtubule-associated protein 7 Gene

Mus musculus

Also known as ste; mshi; mste; MAP-7; Mtap7; E-MAP-115

Gene ID: 17761 | Gene type: protein coding

About Map7

Summary

Enables signaling receptor binding activity. Involved in protein localization to plasma membrane and response to osmotic stress. Acts upstream of or within several processes, including gamete generation; male gonad development; and response to retinoic acid. Located in plasma membrane. Is expressed in several structures, including alimentary system; endocrine gland; ganglia; genitourinary system; and skin. Orthologous to human MAP7 (microtubule associated protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Map7 Products(3)

mRNA	Protein	Name
NM_001198635.1	NP_001185564.1	ensconsin isoform 2
NM_001358787.1	NP_001345716.1	ensconsin isoform 3
NM_008635.2	NP_032661.2	ensconsin isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	14517216	MGI
enables signaling receptor binding	IPI IPI: Inferred from physical interaction	14517216	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within Leydig cell differentiation	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within Sertoli cell development	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within cell morphogenesis	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within cell population proliferation	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within fertilization	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within germ cell development	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within glycosphingolipid metabolic process	IMP IMP: Inferred from mutant phenotype	18308723	MGI
acts upstream of or within homeostasis of number of cells	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within microtubule bundle formation	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within nucleus organization	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within organ growth	IMP IMP: Inferred from mutant phenotype	10837026	MGI
involved in protein localization to plasma membrane	IDA IDA: Inferred from direct assay	14517216	MGI
involved in response to osmotic stress	IDA IDA: Inferred from direct assay	14517216	MGI
acts upstream of or within response to osmotic stress	IPI IPI: Inferred from physical interaction	14517216	MGI
acts upstream of or within response to retinoic acid	IMP IMP: Inferred from mutant phenotype	10837026	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	10837026	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	14517216	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ensconsin

epithelial microtubule-associated protein of 115 kDa

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08087	MAP7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08088	MAP7D1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08089	MAP7D2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08090	MAP7D3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Map7	NCBI	NCBI:9053

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