Myh11 - myosin, heavy polypeptide 11, smooth muscle Gene

Mus musculus

Also known as SM1; SM2; smMHC

Gene ID: 17880 | Gene type: protein coding

About Myh11

Summary

Enables cytoskeletal motor activity. Acts upstream of or within smooth muscle contraction. Located in brush border; smooth muscle contractile fiber; and stress fiber. Part of muscle Myosin complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and liver and biliary system. Human ortholog(s) of this gene implicated in patent ductus arteriosus and thoracic aortic aneurysm. Orthologous to human MYH11 (Myosin heavy chain 11). [provided by Alliance of Genome Resources, Apr 2022]

Myh11 Products(4)

mRNA	Protein	Name
NM_001161775.2	NP_001155247.1	myosin-11 isoform 2
NM_001402795.1	NP_001389724.1	myosin-11 isoform 3
NM_001402796.1	NP_001389725.1	myosin-11 isoform 4
NM_013607.3	NP_038635.2	myosin-11 isoform 1

Protein Preferred Names

Protein Names

myosin-11

myosin heavy chain 11, smooth muscle

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08897	MYH11 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Myh11	NCBI	NCBI:4629

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