Myh2 - myosin, heavy polypeptide 2, skeletal muscle, adult Gene

Also Known as MHC2A; Myh2a; Myhs-f; Myhsf1; Myhs-f1; MyHC-IIa

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17882

Summary

Acts upstream of or within actin-mediated cell contraction; plasma membrane repair; and response to activity. Located in several cellular components, including A band; Golgi apparatus; and actomyosin contractile ring. Is expressed in several structures, including alimentary system; forelimb bud mesenchyme; and skeletal musculature. Human ortholog(s) of this gene implicated in inclusion body myositis and proximal myopathy and ophthalmoplegia. Orthologous to human MYH2 (Myosin heavy chain 2). [provided by Alliance of Genome Resources, Apr 2022]

Myh2 Products (1)

mRNA Protein Name
NM_001039545.2 NP_001034634.2 myosin-2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin-mediated cell contraction IDA
IDA: Inferred from direct assay
22750946 MGI
acts upstream of or within plasma membrane repair IMP
IMP: Inferred from mutant phenotype
14617807 MGI
acts upstream of or within response to muscle activity IDA
IDA: Inferred from direct assay
18310078 MGI
Cellular Component GO Annotation Evidence References Source
located in A band IDA
IDA: Inferred from direct assay
18761673 MGI
located in Golgi apparatus IMP
IMP: Inferred from mutant phenotype
14617807 MGI
located in actomyosin contractile ring IDA
IDA: Inferred from direct assay
15548599 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
23793062 MGI
located in myofibril IDA
IDA: Inferred from direct assay
21884692 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin-2

  • myosin heavy chain 2A

  • skeletal muscle myosin heavy chain II-a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08901 MYH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myh2 NCBI NCBI:4620