Myo1f - myosin IF Gene

Also Known as C330006B10Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 17916

Summary

Predicted to enable actin filament binding activity and microfilament motor activity. Acts upstream of or within several processes, including defense response to Gram-positive bacterium; neutrophil degranulation; and positive regulation of cell migration. Located in cortical actin Cytoskeleton. Part of filamentous actin. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and liver. Orthologous to human MYO1F (Myosin IF). [provided by Alliance of Genome Resources, Apr 2022]

Myo1f Products (1)

mRNA	Protein	Name
NM_053214.2	NP_444444.2	unconventional myosin-If

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within defense response to Gram-positive bacterium	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of or within negative regulation of cell adhesion	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of or within neutrophil degranulation	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of or within neutrophil mediated immunity	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of neutrophil migration	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of or within positive regulation of neutrophil migration	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of or within regulation of actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of or within regulation of innate immune response	IMP IMP: Inferred from mutant phenotype	17023661	MGI
acts upstream of or within response to bacterium	IEP IEP: Inferred from expression pattern	23012479	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in cortical actin cytoskeleton	IDA IDA: Inferred from direct assay	17023661	MGI
part of filamentous actin	IDA IDA: Inferred from direct assay	17023661	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
unconventional myosin-If	myosin-1F-like protein myosin-If

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08942	MYO1F Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Myo1f	NCBI	NCBI:4542