2. Gene
  3. Napb - N-ethylmaleimide sensitive fusion protein attachment protein beta Gene

Napb - N-ethylmaleimide sensitive fusion protein attachment protein beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as I47; E161; Brp14; SNARE; b-SNAP

Gene ID: 17957 | Gene type: protein coding

About Napb

Summary

Enables syntaxin binding activity. Involved in regulation of synaptic vesicle priming. Acts upstream of or within SNARE complex disassembly and glutamatergic synaptic transmission. Located in glutamatergic synapse. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Is expressed in central nervous system; liver; peripheral nervous system ganglion; and retina nuclear layer. Orthologous to human NAPB (NSF attachment protein beta). [provided by Alliance of Genome Resources, Apr 2022]

Napb Products(1)

mRNA Protein Name
NM_019632.4 NP_062606.1 beta-soluble NSF attachment protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21040848 MGI
enables syntaxin binding IDA
IDA: Inferred from direct assay
14755058 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within SNARE complex disassembly IGI
IGI: Inferred from genetic interaction
21040848 MGI
involved in regulation of synaptic vesicle priming IDA
IDA: Inferred from direct assay
21040848 MGI
involved in regulation of synaptic vesicle priming IEP
IEP: Inferred from expression pattern
21040848 MGI
acts upstream of or within regulation of synaptic vesicle priming IGI
IGI: Inferred from genetic interaction
21040848 MGI
involved in regulation of synaptic vesicle priming IMP
IMP: Inferred from mutant phenotype
21040848 MGI
acts upstream of or within synaptic transmission, glutamatergic IGI
IGI: Inferred from genetic interaction
21040848 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21040848 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
21040848 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21040848 MGI
part of synaptobrevin 2-SNAP-25-syntaxin-1a complex IDA
IDA: Inferred from direct assay
21040848 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-soluble NSF attachment protein

N-ethylmaleimide-sensitive factor attachment protein beta

SNAP-beta

brain protein 14

brain protein I47

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09030 NAPB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12685 SEPTIN9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Napb NCBI NCBI:63908