Nkx2-9 - NK2 homeobox 9 Gene

Also Known as Nkx2-8; Nkx2.9; tinman; Nkx-2.9

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18094

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within axonogenesis; lung development; and negative regulation of epithelial cell proliferation. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; embryo mesoderm; liver; and lung epithelium. Orthologous to human NKX2-8 (NK2 homeobox 8). [provided by Alliance of Genome Resources, Apr 2022]

Nkx2-9 Products (2)

mRNA Protein Name
NM_008701.2 NP_032727.2 homeobox protein Nkx-2.8
NM_008701.2 NP_032727.2 homeobox protein Nkx-2.8

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within axonogenesis IMP
IMP: Inferred from mutant phenotype
16267219 MGI
acts upstream of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
17079460 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
17079460 MGI
acts upstream of or within negative regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
17079460 MGI
acts upstream of or within respiratory tube development IMP
IMP: Inferred from mutant phenotype
17079460 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Nkx-2.8

  • Drosophila NK2 transcription factor related, locus 9

  • NK2 transcription factor related, locus 9

  • homeobox protein NK-2 homolog H

  • homeobox protein Nkx-2.9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09332 NKX2-8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown