Cd244a - CD244 molecule A Gene

Also Known as 2B4; C9.1; Ly90; NAIL; Nmrk; Cd244; NKR2B4; SLAMF4; F730046O15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18106

Summary

Predicted to enable MHC class I protein binding activity. Involved in myeloid dendritic cell activation; natural killer cell activation involved in immune response; and positive regulation of lymphocyte proliferation. Located in external side of plasma membrane. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human CD244 (CD244 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd244a Products (1)

mRNA Protein Name
NM_018729.2 NP_061199.2 natural killer cell receptor 2B4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16127454 MGI
Biological Process GO Annotation Evidence References Source
involved in myeloid dendritic cell activation IMP
IMP: Inferred from mutant phenotype
25643613 MGI
involved in natural killer cell activation involved in immune response IMP
IMP: Inferred from mutant phenotype
15905190 MGI
involved in positive regulation of CD8-positive, alpha-beta T cell proliferation IMP
IMP: Inferred from mutant phenotype
11739483 MGI
involved in positive regulation of natural killer cell proliferation IMP
IMP: Inferred from mutant phenotype
15905190 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
10072077 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

natural killer cell receptor 2B4

  • CD244 natural killer cell receptor 2B4

  • NK cell receptor 2B4

  • NK cell type I receptor protein 2B4

  • SLAM family member 4

  • non-MHC restricted killing associated

  • signaling lymphocytic activation molecule 4

Recombinant Cd244a Proteins

Cat. No. Product Name Accession Purity
HY-P72746 2B4/CD244 Protein, Mouse (HEK293, His) Q07763-1 (Q20-N221) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02213 CD244 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24862 Cd244 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown