Nrap - nebulin-related anchoring protein Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18175

Summary

Enables actin binding activity; muscle alpha-actinin binding activity; and vinculin binding activity. Predicted to be involved in cardiac muscle thin filament assembly. Predicted to act upstream of or within actin Cytoskeleton organization. Located in fascia adherens; muscle tendon junction; and myofibril. Is expressed in early conceptus; heart; limb musculature; oocyte; and skeletal muscle. Orthologous to human NRAP (nebulin related anchoring protein). [provided by Alliance of Genome Resources, Apr 2022]

Nrap Products (18)

mRNA Protein Name
NM_001286552.2 NP_001273481.1 nebulin-related-anchoring protein isoform 3
NM_001403176.1 NP_001390105.1 nebulin-related-anchoring protein isoform 4
NM_001403178.1 NP_001390107.1 nebulin-related-anchoring protein isoform 5
NM_001403180.1 NP_001390109.1 nebulin-related-anchoring protein isoform 6
NM_001403184.1 NP_001390113.1 nebulin-related-anchoring protein isoform 7
NM_001403185.1 NP_001390114.1 nebulin-related-anchoring protein isoform 8
NM_001403186.1 NP_001390115.1 nebulin-related-anchoring protein isoform 9
NM_001403187.1 NP_001390116.1 nebulin-related-anchoring protein isoform 10
NM_001403188.1 NP_001390117.1 nebulin-related-anchoring protein isoform 11
NM_001403190.1 NP_001390119.1 nebulin-related-anchoring protein isoform 12
NM_001403191.1 NP_001390120.1 nebulin-related-anchoring protein isoform 13
NM_001403192.1 NP_001390121.1 nebulin-related-anchoring protein isoform 14
NM_001403193.1 NP_001390122.1 nebulin-related-anchoring protein isoform 15
NM_001403194.1 NP_001390123.1 nebulin-related-anchoring protein isoform 16
NM_001403195.1 NP_001390124.1 nebulin-related-anchoring protein isoform 17
NM_001403196.1 NP_001390125.1 nebulin-related-anchoring protein isoform 18
NM_008733.5 NP_032759.3 nebulin-related-anchoring protein isoform S
NM_198059.4 NP_932307.2 nebulin-related-anchoring protein isoform C

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
9295142 MGI
enables muscle alpha-actinin binding IDA
IDA: Inferred from direct assay
10320340 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10320340 MGI
enables vinculin binding IPI
IPI: Inferred from physical interaction
10320340 MGI
Cellular Component GO Annotation Evidence References Source
located in fascia adherens IDA
IDA: Inferred from direct assay
9295142 MGI
located in muscle tendon junction IDA
IDA: Inferred from direct assay
9295142 MGI
located in myofibril IDA
IDA: Inferred from direct assay
11732910 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nebulin-related-anchoring protein

  • N-RAP

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09416 NOL6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09556 NRAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrap NCBI NCBI:4892