Nsg1 - neuron specific gene family member 1 Gene

Also Known as p21; m234; Neep21

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18196

Summary

Predicted to enable clathrin light chain binding activity and signaling receptor binding activity. Involved in several processes, including amyloid precursor protein metabolic process; neurotransmitter receptor transport; and receptor recycling. Located in several cellular components, including glutamatergic synapse; late endosome; and lateral plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; peripheral nervous system ganglion; and sensory organ. Orthologous to human NSG1 (neuronal vesicle trafficking associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Nsg1 Products (4)

mRNA Protein Name
NM_001359090.1 NP_001346019.1 neuronal vesicle trafficking-associated protein 1
NM_001359091.1 NP_001346020.1 neuronal vesicle trafficking-associated protein 1
NM_001359092.1 NP_001346021.1 neuronal vesicle trafficking-associated protein 1
NM_010942.4 NP_035072.2 neuronal vesicle trafficking-associated protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12070131 MGI
Biological Process GO Annotation Evidence References Source
involved in amyloid precursor protein metabolic process IDA
IDA: Inferred from direct assay
21084623 MGI
involved in neurotransmitter receptor cycle IDA
IDA: Inferred from direct assay
16037816 MGI
involved in neurotransmitter receptor transport, endosome to postsynaptic membrane IDA
IDA: Inferred from direct assay
16037816 MGI
involved in neurotransmitter receptor transport, endosome to postsynaptic membrane IMP
IMP: Inferred from mutant phenotype
16037816 MGI
involved in receptor recycling IMP
IMP: Inferred from mutant phenotype
12070131 MGI
involved in vesicle-mediated transport in synapse IDA
IDA: Inferred from direct assay
16037816 MGI
involved in vesicle-mediated transport in synapse IMP
IMP: Inferred from mutant phenotype
16037816 MGI
Cellular Component GO Annotation Evidence References Source
located in endosome IDA
IDA: Inferred from direct assay
19063943 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
16037816 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
16037816 MGI
located in late endosome IDA
IDA: Inferred from direct assay
28874679 MGI
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
19063943 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
19063943 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal vesicle trafficking-associated protein 1

  • brain neuron cytoplasmic protein 1

  • neuron-enriched endosomal protein of 21 kDa

  • neuron-specific protein family member 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09593 NSG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsg1 NCBI NCBI:27065