EPYC - epiphycan Gene

Homo sapiens

Also known as PGLB; DSPG3; Pg-Lb; SLRR3B

Gene ID: 1833 | Gene type: protein coding

About EPYC

Cytogenetic location: 12q21.33 Genomic coordinates (GRCh38): 12:90,963,682-91,004,972 (from NCBI)

This gene has 3 transcripts (splice variants), 203 orthologues and 10 paralogues. Biased expression in placenta (RPKM 4.1), endometrium (RPKM 0.8) and 1 other tissue.

Summary

Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins. [provided by RefSeq, Jul 2008]

EPYC Products(1)

mRNA	Protein	Name
NM_004950.5	NP_004941.2	epiphycan precursor

EPYC Protein Structure

LRRNT

LRR_8

LRR_6

0
100
200
300
322 a.a.

Protein Preferred Names

Protein Names

epiphycan

dermatan sulfate proteoglycan 3

Recombinant EPYC Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76323	DSPG3/Epiphycan Protein, Human (HEK293, His)	Q99645 (A20-V322)	≥95%

Related Diseases

Diseases

Alias

Corneal Dystrophy, Posterior Amorphous

Posterior Amorphous Corneal Dystrophy	PACD
Chromosome 12q21.33 Deletion Syndrome	Posterior Amorphous Stromal Dystrophy

Cornea Plana

Flat Cornea

Breast Apocrine Carcinoma

Apocrine Carcinoma Of Breast

Apocrine Breast Carcinoma

Stromal Dystrophy

Myopia

Near-Sightedness	Short-Sightedness
Nearsightedness	Nearsighted
Near Vision	Close Sighted
Myopic	Short-Sighted
Near Sighted

Corneal Dystrophy, Congenital Stromal

Congenital Stromal Corneal Dystrophy	CSCD
Congenital Hereditary Stromal Dystrophy	Congenital Hereditary Stromal Dystrophy Of The Cornea
Congenital Stromal Dystrophy Of The Cornea	Dacs
Decorin-Associated Congenital Stromal Corneal Dystrophy	Dystrophia Corneae Parenchymatosa Congenita
Witschel Dystrophy	Dystrophy, Corneal, Stromal, Congenital

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04460	EPYC Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	EPYC	RGD	RGD:1305904
Canis familiaris	EPYC	VGNC	VGNC:40431
Bos taurus	EPYC	VGNC	VGNC:28558
Felis catus	EPYC	VGNC	VGNC:61924
Mus musculus	EPYC	MGD	MGI:107942
Macaca mulatta	EPYC	VGNC	VGNC:72145
Others	EPYC	NCBI