EPYC - epiphycan Gene

Also Known as PGLB; DSPG3; Pg-Lb; SLRR3B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1833

About EPYC

Cytogenetic location: 12q21.33 Genomic coordinates (GRCh38): 12:90,963,682-91,004,972 (from NCBI)

This gene has 3 transcripts (splice variants), 203 orthologues and 10 paralogues. Biased expression in placenta (RPKM 4.1), endometrium (RPKM 0.8) and 1 other tissue.

Summary

Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with Collagen fibrils and Other extracellular matrix proteins. [provided by RefSeq, Jul 2008]

EPYC Products (1)

mRNA Protein Name
NM_004950.5 NP_004941.2 epiphycan precursor

EPYC Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (121 - 142)

LRR_8

LRR_8: Leucine rich repeat (152 - 203)

LRR_6

LRR_6: Leucine Rich repeat (211 - 229)

  • 0
  • 100
  • 200
  • 300
  • 322 a.a.
Protein Preferred Names Protein Names

epiphycan

  • dermatan sulfate proteoglycan 3

Recombinant EPYC Proteins

Cat. No. Product Name Accession Purity
HY-P76323 DSPG3/Epiphycan Protein, Human (HEK293, His) Q99645 (A20-V322) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Corneal Dystrophy, Posterior Amorphous

  • Posterior Amorphous Corneal Dystrophy

  • PACD

  • Chromosome 12q21.33 Deletion Syndrome

  • Posterior Amorphous Stromal Dystrophy
Cornea Plana

  • Flat Cornea
Breast Apocrine Carcinoma

  • Apocrine Carcinoma Of Breast

  • Apocrine Breast Carcinoma
Stromal Dystrophy
Myopia

  • Near-Sightedness

  • Short-Sightedness

  • Nearsightedness

  • Nearsighted

  • Near Vision

  • Close Sighted

  • Myopic

  • Short-Sighted

  • Near Sighted
Corneal Dystrophy, Congenital Stromal

  • Congenital Stromal Corneal Dystrophy

  • CSCD

  • Congenital Hereditary Stromal Dystrophy

  • Congenital Hereditary Stromal Dystrophy Of The Cornea

  • Congenital Stromal Dystrophy Of The Cornea

  • Dacs

  • Decorin-Associated Congenital Stromal Corneal Dystrophy

  • Dystrophia Corneae Parenchymatosa Congenita

  • Witschel Dystrophy

  • Dystrophy, Corneal, Stromal, Congenital
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04460 EPYC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19131 Epyc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25621 Epyc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EPYC RGD RGD:1305904
Canis familiaris EPYC VGNC VGNC:40431
Bos taurus EPYC VGNC VGNC:28558
Felis catus EPYC VGNC VGNC:61924
Mus musculus EPYC MGD MGI:107942
Macaca mulatta EPYC VGNC VGNC:72145
Others EPYC NCBI