2. Gene
  3. Otp - orthopedia homeobox Gene

Otp - orthopedia homeobox Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 18420 | Gene type: protein coding

About Otp

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within forebrain development and positive regulation of neuroblast proliferation. Predicted to be located in fibrillar center and nuclear body. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human OTP (orthopedia homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Otp Products(1)

mRNA Protein Name
NM_011021.5 NP_035151.1 homeobox protein orthopedia
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within dopaminergic neuron differentiation IMP
IMP: Inferred from mutant phenotype
17481897 MGI
acts upstream of or within forebrain neuron differentiation IMP
IMP: Inferred from mutant phenotype
17481897 MGI
acts upstream of or within hypothalamus cell differentiation IMP
IMP: Inferred from mutant phenotype
10557207 MGI
acts upstream of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
10557207 MGI
acts upstream of or within neuroendocrine cell differentiation IMP
IMP: Inferred from mutant phenotype
10557207 MGI
acts upstream of or within neurohypophysis development IMP
IMP: Inferred from mutant phenotype
10557207 MGI
acts upstream of or within positive regulation of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
10557207 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein orthopedia

orthopedia homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09868 OTP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Otp NCBI NCBI:23440