1. Gene
  2. Pbx2 - pre B cell leukemia homeobox 2 Gene

Pbx2 - pre B cell leukemia homeobox 2 Gene

Mus musculus

Also known as G17

Gene ID: 18515 | Gene type: protein coding

About Pbx2

Summary

Enables chromatin binding activity. Acts upstream of or within embryonic limb morphogenesis; positive regulation of transcription by RNA polymerase II; and proximal/distal pattern formation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; eye; and genitourinary system. Orthologous to human PBX2 (PBX homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Pbx2 Products(1)

mRNA Protein Name
NM_017463.3 NP_059491.1 pre-B-cell leukemia transcription factor 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
16672333 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10381567 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within embryonic limb morphogenesis IGI
IGI: Inferred from genetic interaction
16672333 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16672333 MGI
acts upstream of or within proximal/distal pattern formation IGI
IGI: Inferred from genetic interaction
16672333 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
10842069 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
10381567 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-B-cell leukemia transcription factor 2

homeobox protein PBX2

Orthologs Information

Species Symbol Source ID
Homo sapiens Pbx2 NCBI NCBI:5089