Pla2r1 - phospholipase A2 receptor 1 Gene

Also Known as Pla2r; Pla2-r; Pla2g1br

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18779

Summary

Enables Phospholipase binding activity. Involved in negative regulation of Phospholipase A2 activity; receptor-mediated endocytosis; and regulation of arachidonic acid secretion. Located in extracellular region. Is expressed in central nervous system and sensory organ. Orthologous to human PLA2R1 (Phospholipase A2 receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Pla2r1 Products (1)

mRNA Protein Name
NM_008867.2 NP_032893.1 secretory phospholipase A2 receptor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phospholipase binding IPI
IPI: Inferred from physical interaction
7925459 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of arachidonate secretion IDA
IDA: Inferred from direct assay
11830583 MGI
involved in negative regulation of phospholipase A2 activity IDA
IDA: Inferred from direct assay
11830583 MGI
involved in positive regulation of arachidonate secretion IDA
IDA: Inferred from direct assay
10946309 MGI
involved in receptor-mediated endocytosis IDA
IDA: Inferred from direct assay
7925459 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
11830583 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

secretory phospholipase A2 receptor

  • 180 kDa secretory phospholipase A2 receptor

  • M-type receptor

  • PLA2-I receptor

  • phospholipase A2, group IB, pancreas, receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10635 PLA2R1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2r1 NCBI NCBI:22925