Plaa - phospholipase A2, activating protein Gene

Also Known as PLAP; Ufd3; PLA2P; 2410007N06; D4Ertd618e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18786

Summary

Enables Phospholipase A2 activator activity. Involved in several processes, including negative regulation of protein K63-linked ubiquitination; positive regulation of dendrite extension; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Acts upstream of or within inflammatory response. Located in cytoplasm; nucleus; and synapse. Orthologous to human PLAA (Phospholipase A2 activating protein). [provided by Alliance of Genome Resources, Apr 2022]

Plaa Products (1)

mRNA Protein Name
NM_172695.2 NP_766283.2 phospholipase A-2-activating protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phospholipase A2 activator activity IDA
IDA: Inferred from direct assay
2052621 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11689694 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inflammatory response IDA
IDA: Inferred from direct assay
2052621 MGI
involved in negative regulation of protein K63-linked ubiquitination IMP
IMP: Inferred from mutant phenotype
28413018 MGI
involved in positive regulation of dendrite extension IMP
IMP: Inferred from mutant phenotype
28413018 MGI
involved in positive regulation of neuron migration IMP
IMP: Inferred from mutant phenotype
28413018 MGI
involved in positive regulation of synaptic vesicle recycling IMP
IMP: Inferred from mutant phenotype
28413018 MGI
involved in prostaglandin metabolic process IMP
IMP: Inferred from mutant phenotype
28007986 MGI
involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IMP
IMP: Inferred from mutant phenotype
28413018 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
28413018 MGI
located in nucleus IDA
IDA: Inferred from direct assay
28413018 MGI
located in synapse IDA
IDA: Inferred from direct assay
28413018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipase A-2-activating protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10636 PLAA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plaa NCBI NCBI:9373