Plcb4 - phospholipase C, beta 4 Gene

Also Known as A930039J07Rik; C230058B11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18798

Summary

Predicted to enable mitogen-activated protein kinase binding activity and phosphatidylinositol Phospholipase C activity. Involved in modulation of chemical synaptic transmission. Located in several cellular components, including glutamatergic synapse; parallel fiber to Purkinje cell synapse; and smooth endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PLCB4 (Phospholipase C beta 4). [provided by Alliance of Genome Resources, Apr 2022]

Plcb4 Products (5)

mRNA Protein Name
NM_001355153.1 NP_001342082.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform a
NM_001355154.1 NP_001342083.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform b
NM_001355155.1 NP_001342084.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform c
NM_001355156.1 NP_001342085.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform d
NM_013829.3 NP_038857.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15579147 MGI
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
11551922 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
11551922 MGI
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
15579147 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11551922 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
11551922 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15579147 MGI
is active in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
11551922 MGI
is active in parallel fiber to Purkinje cell synapse IMP
IMP: Inferred from mutant phenotype
11551922 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
15579147 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
15579147 MGI
is active in postsynaptic density IDA
IDA: Inferred from direct assay
15579147 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
15579147 MGI
is active in postsynaptic density IEP
IEP: Inferred from expression pattern
15579147 MGI
is active in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
15579147 MGI
located in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
15579147 MGI
is active in smooth endoplasmic reticulum IEP
IEP: Inferred from expression pattern
15579147 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11540 CCKBR agonist-1 98.48% Unkown
HY-RS10655 PLCB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plcb4 NCBI NCBI:5332