Pou2af1 - POU domain, class 2, associating factor 1 Gene

Also Known as Bob1; OCAB; BOB.1; Bob-1; OBF-1; OBF.1; OCA-B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18985

Summary

Enables DNA binding activity and transcription coactivator activity. Involved in cellular response to virus; germinal center B cell differentiation; and positive regulation of interleukin-6 production. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human POU2AF1 (POU class 2 homeobox associating factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou2af1 Products (1)

mRNA Protein Name
NM_011136.2 NP_035266.1 POU domain class 2-associating factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
11937630 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10329190 MGI
enables transcription coactivator activity IDA
IDA: Inferred from direct assay
23045607 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to virus IMP
IMP: Inferred from mutant phenotype
23045607 MGI
involved in germinal center B cell differentiation IMP
IMP: Inferred from mutant phenotype
23045607 MGI
involved in positive regulation of interleukin-6 production IDA
IDA: Inferred from direct assay
23045607 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POU domain class 2-associating factor 1

  • B-cell-specific coactivator OBF-1

  • OCT-binding factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10896 POU2AF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou2af1 NCBI NCBI:5450