Pou2af1 - POU domain, class 2, associating factor 1 Gene

Mus musculus

Also known as Bob1; OCAB; BOB.1; Bob-1; OBF-1; OBF.1; OCA-B

Gene ID: 18985 | Gene type: protein coding

About Pou2af1

Summary

Enables DNA binding activity and transcription coactivator activity. Involved in cellular response to virus; germinal center B cell differentiation; and positive regulation of interleukin-6 production. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human POU2AF1 (POU class 2 homeobox associating factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou2af1 Products(1)

mRNA	Protein	Name
NM_011136.2	NP_035266.1	POU domain class 2-associating factor 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	11937630	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	10329190	MGI
enables transcription coactivator activity	IDA IDA: Inferred from direct assay	23045607	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to virus	IMP IMP: Inferred from mutant phenotype	23045607	MGI
involved in germinal center B cell differentiation	IMP IMP: Inferred from mutant phenotype	23045607	MGI
involved in positive regulation of interleukin-6 production	IDA IDA: Inferred from direct assay	23045607	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

POU domain class 2-associating factor 1

B-cell-specific coactivator OBF-1

OCT-binding factor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10896	POU2AF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pou2af1	NCBI	NCBI:5450

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