Pou3f1 - POU domain, class 3, transcription factor 1 Gene

Mus musculus

Also known as Oct6; Otf6; Scip; Tst1; Oct-6; Otf-6; Test1; Tst-1

Gene ID: 18991 | Gene type: protein coding

About Pou3f1

Summary

Enables DNA binding activity. Involved in positive regulation of gene expression and positive regulation of transcription, DNA-templated. Acts upstream of or within forebrain development; keratinocyte differentiation; and myelination in peripheral nervous system. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; sensory organ; and urinary system. Orthologous to human POU3F1 (POU class 3 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou3f1 Products(1)

mRNA	Protein	Name
NM_011141.2	NP_035271.1	POU domain, class 3, transcription factor 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	12782656	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within Schwann cell development	IMP IMP: Inferred from mutant phenotype	12782656	MGI
acts upstream of or within epidermis development	IGI IGI: Inferred from genetic interaction	9242494	MGI
acts upstream of or within forebrain development	IMP IMP: Inferred from mutant phenotype	19527706	MGI
acts upstream of or within keratinocyte differentiation	IGI IGI: Inferred from genetic interaction	9242494	MGI
acts upstream of or within myelination	IMP IMP: Inferred from mutant phenotype	15282162	MGI
acts upstream of or within myelination in peripheral nervous system	IGI IGI: Inferred from genetic interaction	12782656	MGI
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	15713637	MGI
involved in positive regulation of gene expression	IDA IDA: Inferred from direct assay	15713637	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	15713637	MGI
part of transcription regulator complex	IDA IDA: Inferred from direct assay	12782656	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

POU domain, class 3, transcription factor 1

POU domain transcription factor SCIP	octamer binding factor oct6
octamer-binding protein 6	octamer-binding transcription factor 6

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10900	POU3F1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pou3f1	NCBI	NCBI:5453

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