Pou3f1 - POU domain, class 3, transcription factor 1 Gene

Also Known as Oct6; Otf6; Scip; Tst1; Oct-6; Otf-6; Test1; Tst-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18991

Summary

Enables DNA binding activity. Involved in positive regulation of gene expression and positive regulation of transcription, DNA-templated. Acts upstream of or within forebrain development; keratinocyte differentiation; and myelination in peripheral nervous system. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; sensory organ; and urinary system. Orthologous to human POU3F1 (POU class 3 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou3f1 Products (1)

mRNA Protein Name
NM_011141.2 NP_035271.1 POU domain, class 3, transcription factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12782656 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Schwann cell development IMP
IMP: Inferred from mutant phenotype
12782656 MGI
acts upstream of or within epidermis development IGI
IGI: Inferred from genetic interaction
9242494 MGI
acts upstream of or within forebrain development IMP
IMP: Inferred from mutant phenotype
19527706 MGI
acts upstream of or within keratinocyte differentiation IGI
IGI: Inferred from genetic interaction
9242494 MGI
acts upstream of or within myelination IMP
IMP: Inferred from mutant phenotype
15282162 MGI
acts upstream of or within myelination in peripheral nervous system IGI
IGI: Inferred from genetic interaction
12782656 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15713637 MGI
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
15713637 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15713637 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
12782656 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POU domain, class 3, transcription factor 1

  • POU domain transcription factor SCIP

  • octamer binding factor oct6

  • octamer-binding protein 6

  • octamer-binding transcription factor 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10900 POU3F1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou3f1 NCBI NCBI:5453