Plpp1 - phospholipid phosphatase 1 Gene

Also Known as LPP1; mPAP; Hic53; LPP-1; PAP2a; Hpic53; PAP-2a; Ppap2a; PAP2-alpha

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19012

Summary

Enables diacylglycerol diphosphate Phosphatase activity; lipid Phosphatase activity; and phosphatidate Phosphatase activity. Involved in several processes, including phospholipid dephosphorylation; phospholipid metabolic process; and sphingolipid metabolic process. Located in caveola. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human PLPP1 (phospholipid Phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Plpp1 Products (2)

mRNA Protein Name
NM_008247.3 NP_032273.1 phospholipid phosphatase 1 isoform 1
NM_008903.2 NP_032929.1 phospholipid phosphatase 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ceramide-1-phosphate phosphatase activity IDA
IDA: Inferred from direct assay
10359651 MGI
enables diacylglycerol diphosphate phosphatase activity IDA
IDA: Inferred from direct assay
10359651 MGI
enables diacylglycerol diphosphate phosphatase activity IMP
IMP: Inferred from mutant phenotype
19215222 MGI
enables lipid phosphatase activity IDA
IDA: Inferred from direct assay
15461590 MGI
enables phosphatidate phosphatase activity IDA
IDA: Inferred from direct assay
8702556 MGI
enables phosphatidate phosphatase activity IMP
IMP: Inferred from mutant phenotype
19215222 MGI
enables sphingosine-1-phosphate phosphatase activity IDA
IDA: Inferred from direct assay
10359651 MGI
Biological Process GO Annotation Evidence References Source
involved in ceramide metabolic process IDA
IDA: Inferred from direct assay
10359651 MGI
involved in phospholipid dephosphorylation IDA
IDA: Inferred from direct assay
10359651 MGI
involved in phospholipid dephosphorylation IMP
IMP: Inferred from mutant phenotype
19215222 MGI
involved in phospholipid metabolic process IDA
IDA: Inferred from direct assay
10359651 MGI
involved in signal transduction IMP
IMP: Inferred from mutant phenotype
10359651 MGI
involved in sphingosine metabolic process IDA
IDA: Inferred from direct assay
10359651 MGI
Cellular Component GO Annotation Evidence References Source
located in caveola IDA
IDA: Inferred from direct assay
11535125 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
19215222 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipid phosphatase 1

  • 35 kDa PAP

  • hydrogen peroxide inducible protein 53

  • lipid phosphate phosphohydrolase 1

  • phosphatidate phosphohydrolase type 2a

  • phosphatidic acid phosphatase 2a

  • phosphatidic acid phosphatase type 2A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10734 PLPP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plpp1 NCBI NCBI:8611