2. Gene
  3. Ppp3cb - protein phosphatase 3, catalytic subunit, beta isoform Gene

Ppp3cb - protein phosphatase 3, catalytic subunit, beta isoform Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cnab; Calnb; CnAbeta; 1110063J16Rik

Gene ID: 19056 | Gene type: protein coding

About Ppp3cb

Summary

Enables calmodulin-dependent protein Phosphatase activity. Involved in several processes, including calcium-ion regulated exocytosis; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and regulation of synaptic vesicle endocytosis. Acts upstream of or within several processes, including circulatory system development; locomotion involved in locomotory behavior; and negative regulation of T cell mediated cytotoxicity. Located in T-tubule and Z disc. Is active in glutamatergic synapse. Is expressed in several structures, including gastrocnemius muscle; jaw skeleton; ovary; renal vasculature; and tooth. Human ortholog(s) of this gene implicated in aortic valve stenosis. Orthologous to human PPP3CB (protein Phosphatase 3 catalytic subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp3cb Products(3)

mRNA Protein Name
NM_001310426.1 NP_001297355.1 serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform 2
NM_001310427.1 NP_001297356.1 serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform 3
NM_008914.3 NP_032940.1 serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform 1
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

CAM-PRP catalytic subunit

CNA beta

PP2BA beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11024 PPP3CB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp3cb NCBI NCBI:5532