2. Gene
  3. Prph - peripherin Gene

Prph - peripherin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Prph1

Gene ID: 19132 | Gene type: protein coding

About Prph

Summary

Predicted to enable structural molecule activity. Acts upstream of or within intermediate filament Cytoskeleton organization. Located in C-fiber; intermediate filament; and photoreceptor outer segment membrane. Is expressed in several structures, including alimentary system; nervous system; and olfactory system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 1. Orthologous to human PRPH (peripherin). [provided by Alliance of Genome Resources, Apr 2022]

Prph Products(5)

mRNA Protein Name
NM_001163588.2 NP_001157060.1 peripherin isoform 2
NM_001163589.2 NP_001157061.1 peripherin isoform 3
NM_001411661.1 NP_001398590.1 peripherin isoform 4
NM_001411662.1 NP_001398591.1 peripherin isoform 5
NM_013639.3 NP_038667.2 peripherin isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12403814 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within intermediate filament cytoskeleton organization IDA
IDA: Inferred from direct assay
12642616 MGI
Cellular Component GO Annotation Evidence Reference Source
located in C-fiber IDA
IDA: Inferred from direct assay
16029194 MGI
located in axon IDA
IDA: Inferred from direct assay
12107488 MGI
located in intermediate filament IDA
IDA: Inferred from direct assay
12642616 MGI
located in neurofilament IDA
IDA: Inferred from direct assay
10221457 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
22183407 MGI
located in photoreceptor outer segment membrane IDA
IDA: Inferred from direct assay
10414956 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peripherin

peripherin 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11217 PRPH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11218 PRPH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prph NCBI NCBI:5630