2. Gene
  3. Cyth1 - cytohesin 1 Gene

Cyth1 - cytohesin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CLM1; CTH-1; CYTIP; Pscd1

Gene ID: 19157 | Gene type: protein coding

About Cyth1

Summary

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within establishment of epithelial cell polarity. Located in bicellular tight junction; cytosol; and plasma membrane. Is extrinsic component of cytoplasmic side of plasma membrane. Is expressed in brain; sciatic nerve; and spinal cord. Orthologous to human CYTH1 (cytohesin 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyth1 Products(7)

mRNA Protein Name
NM_001112699.2 NP_001106169.1 cytohesin-1 isoform 2
NM_001112700.2 NP_001106170.1 cytohesin-1 isoform 3
NM_001378885.1 NP_001365814.1 cytohesin-1 isoform 4
NM_001378886.1 NP_001365815.1 cytohesin-1 isoform 5
NM_001378887.1 NP_001365816.1 cytohesin-1 isoform 6
NM_001378888.1 NP_001365817.1 cytohesin-1 isoform 7
NM_011180.4 NP_035310.2 cytohesin-1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
18042453 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20080746 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within establishment of epithelial cell polarity IMP
IMP: Inferred from mutant phenotype
20080746 MGI
Cellular Component GO Annotation Evidence Reference Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
20080746 MGI
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
18042453 MGI
located in cytosol IDA
IDA: Inferred from direct assay
18042453 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
29420262 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytohesin-1

PH, SEC7 and coiled-coil domain-containing protein 1

SEC7 homolog A

mSec7-1

pleckstrin homology, Sec7 and coiled-coil domains 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03501 CYTH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyth1 NCBI NCBI:9267