Grin3a - glutamate ionotropic receptor NMDA type subunit 3A Gene

Also Known as NR3; chi-1; GluN3A

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 191573

Summary

Enables several functions, including glycine binding activity; ionotropic glutamate receptor activity; and protein Phosphatase 2A binding activity. Contributes to NMDA glutamate receptor activity. Involved in several processes, including calcium ion transport; ionotropic glutamate receptor signaling pathway; and negative regulation of dendritic spine development. Located in postsynaptic membrane. Part of NMDA selective glutamate receptor complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Orthologous to human GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A). [provided by Alliance of Genome Resources, Apr 2022]

Grin3a Products (2)

mRNA Protein Name
NM_001198583.2 NP_001185512.1 glutamate receptor ionotropic, NMDA 3A isoform 2 precursor
NM_138546.2 NP_612555.1 glutamate receptor ionotropic, NMDA 3A isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to NMDA glutamate receptor activity IDA
IDA: Inferred from direct assay
17182766 RGD
enables NMDA glutamate receptor activity IDA
IDA: Inferred from direct assay
16477151 RGD
enables glutamate-gated receptor activity IDA
IDA: Inferred from direct assay
16477151 RGD
enables glycine binding IDA
IDA: Inferred from direct assay
17182766 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17658481 RGD
enables protein phosphatase 2A binding IDA
IDA: Inferred from direct assay
15194871 RGD
Biological Process GO Annotation Evidence References Source
involved in calcium ion transport IDA
IDA: Inferred from direct assay
17182766 RGD
involved in ionotropic glutamate receptor signaling pathway IDA
IDA: Inferred from direct assay
16477151 RGD
involved in negative regulation of dendritic spine development IDA
IDA: Inferred from direct assay
24297929 RGD
involved in neuron development IEP
IEP: Inferred from expression pattern
16477151 RGD
involved in rhythmic process IDA
IDA: Inferred from direct assay
16477151 RGD
Cellular Component GO Annotation Evidence References Source
part of NMDA selective glutamate receptor complex IDA
IDA: Inferred from direct assay
16477151 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
16477151 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
16617342 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
16617342 RGD
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
15194871 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamate receptor ionotropic, NMDA 3A

  • N-methyl-D-aspartate receptor subtype 3A

  • NMDAR-L

  • NMDAR-L1

  • NMDAR3A

  • NR3 chi-1

  • NR3A

  • glutamate [NMDA] receptor subunit 3A

  • glutamate receptor chi-1

  • glutamate receptor, ionotropic, N-methyl-D-aspartate 3A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05806 GRIN3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grin3a NCBI NCBI:116443