Pou3f3 - POU class 3 homeobox 3 Gene

Also Known as Brn1; RHS1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192109

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in positive regulation of gene expression and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human POU3F3 (POU class 3 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Pou3f3 Products (1)

mRNA Protein Name
NM_138837.2 NP_620192.2 POU domain, class 3, transcription factor 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
9405434 RGD
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
9632656 RGD
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
9632656 RGD
acts upstream of or within positive regulation of DNA-templated transcription IGI
IGI: Inferred from genetic interaction
9632656 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
15713637 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
15713637 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9405434 RGD
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
9632656 RGD
located in nucleus IMP
IMP: Inferred from mutant phenotype
15713637 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POU domain, class 3, transcription factor 3

  • brain-1

  • brain-specific homeobox/POU domain protein 1

  • brn-1 protein

  • class III POU protein POU-domain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10902 POU3F3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou3f3 NCBI NCBI:5455