DAB2IP - Dab2ip DAB2 interacting protein Gene

Also Known as AIP-1; DIP1/2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192126

Summary

Enables GTPase activator activity and protein N-terminus binding activity. Involved in cellular response to epidermal growth factor stimulus; negative regulation of cell growth; and negative regulation of signal transduction. Predicted to be located in axon; endocytic vesicle; and neuronal cell body membrane. Predicted to be part of AIP1-IRE1 complex. Orthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

DAB2IP Products (1)

mRNA Protein Name
NM_138710.4 NP_619724.3 disabled homolog 2-interacting protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
11812785 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11812785 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to epidermal growth factor stimulus IDA
IDA: Inferred from direct assay
11812785 RGD
involved in negative regulation of Ras protein signal transduction IDA
IDA: Inferred from direct assay
11812785 RGD
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
11812785 RGD
involved in negative regulation of epidermal growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
11812785 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disabled homolog 2-interacting protein

  • ASK-interacting protein 1

  • DOC-2/DAB2 interactive protein

  • DOC2/DAB2 interactive protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03512 DAB2IP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DAB2IP NCBI NCBI:153090