2. Gene
  3. DAB2IP - Dab2ip DAB2 interacting protein Gene

DAB2IP - Dab2ip DAB2 interacting protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as AIP-1; DIP1/2

Gene ID: 192126 | Gene type: protein coding

About DAB2IP

Summary

Enables GTPase activator activity and protein N-terminus binding activity. Involved in cellular response to epidermal growth factor stimulus; negative regulation of cell growth; and negative regulation of signal transduction. Predicted to be located in axon; endocytic vesicle; and neuronal cell body membrane. Predicted to be part of AIP1-IRE1 complex. Orthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

DAB2IP Products(1)

mRNA Protein Name
NM_138710.4 NP_619724.3 disabled homolog 2-interacting protein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
11812785 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11812785 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to epidermal growth factor stimulus IDA
IDA: Inferred from direct assay
11812785 RGD
involved in negative regulation of Ras protein signal transduction IDA
IDA: Inferred from direct assay
11812785 RGD
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
11812785 RGD
involved in negative regulation of epidermal growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
11812785 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disabled homolog 2-interacting protein

ASK-interacting protein 1

DOC-2/DAB2 interactive protein

DOC2/DAB2 interactive protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03512 DAB2IP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DAB2IP NCBI NCBI:153090