Socs7 - suppressor of cytokine signaling 7 Gene

Also Known as Nap4; 2310063P06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 192157

Summary

Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within several processes, including brain development; fat cell differentiation; and Insulin Receptor signaling pathway. Predicted to be located in cytosol. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including brain; eye; metanephros; and testis. Orthologous to human SOCS7 (suppressor of cytokine signaling 7). [provided by Alliance of Genome Resources, Apr 2022]

Socs7 Products (1)

mRNA Protein Name
NM_138657.4 NP_619598.2 suppressor of cytokine signaling 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphorylation-dependent protein binding IDA
IDA: Inferred from direct assay
24210661 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24210661 MGI
enables ubiquitin-like ligase-substrate adaptor activity IDA
IDA: Inferred from direct assay
24210661 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebral cortex radially oriented cell migration IMP
IMP: Inferred from mutant phenotype
24210661 MGI
acts upstream of or within fat cell differentiation IMP
IMP: Inferred from mutant phenotype
16127460 MGI
acts upstream of or within insulin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
16127460 MGI
acts upstream of or within layer formation in cerebral cortex IMP
IMP: Inferred from mutant phenotype
24210661 MGI
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
24210661 MGI
acts upstream of or within protein ubiquitination IDA
IDA: Inferred from direct assay
16127460 MGI
acts upstream of or within protein ubiquitination IGI
IGI: Inferred from genetic interaction
24210661 MGI
acts upstream of or within radial glia guided migration of Purkinje cell IMP
IMP: Inferred from mutant phenotype
24210661 MGI
Cellular Component GO Annotation Evidence References Source
part of Cul5-RING ubiquitin ligase complex IDA
IDA: Inferred from direct assay
24210661 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

suppressor of cytokine signaling 7

  • Nck, Ash and phospholipase C binding protein

  • SH2 domain containing SOCS box protein SOCS7

  • SOCS-7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13555 SOCS4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13558 SOCS7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Socs7 NCBI NCBI:30837