Ptger2 - prostaglandin E receptor 2 (subtype EP2) Gene

Also Known as EP2; Ptgerep2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19217

Summary

Predicted to enable prostaglandin E receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to prostaglandin E stimulus; and response to progesterone. Acts upstream of or within regulation of cell population proliferation and response to lipopolysaccharide. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; gut; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Orthologous to human PTGER2 (prostaglandin E receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ptger2 Products (1)

mRNA Protein Name
NM_008964.4 NP_032990.1 prostaglandin E2 receptor EP2 subtype

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
18403039 MGI
involved in cellular response to prostaglandin E stimulus IDA
IDA: Inferred from direct assay
18403039 MGI
acts upstream of or within interleukin-33 production IMP
IMP: Inferred from mutant phenotype
32484881 MGI
acts upstream of or within regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
11533709 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
15834430 MGI
acts upstream of or within response to nematode IMP
IMP: Inferred from mutant phenotype
32484881 MGI
involved in response to progesterone IDA
IDA: Inferred from direct assay
10684792 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostaglandin E2 receptor EP2 subtype

  • EP2 receptor

  • PGE receptor EP2 subtype

  • PGE2 receptor EP2 subtype

  • prostaglandin E receptor 2 (EP2 subtype)

  • prostaglandin E receptor EP2 subtype

  • prostaglandin E receptor subtype EP2

  • prostanoid EP2 receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108560 (+)-Fluprostenol Activator / Unkown
HY-RS11376 PTGER2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-108560A 15(S)-Fluprostenol Activator / Unkown
HY-108560S (+)-Fluprostenol-d4 Activator / Unkown
HY-RS19072 Ptger2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25562 Ptger2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptger2 NCBI NCBI:5732