PTGER2 - prostaglandin E receptor 2 Gene

Also Known as EP2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5732

About PTGER2

Cytogenetic location: 14q22.1 Genomic coordinates (GRCh38): 14:52,314,312-52,328,598 (from NCBI)

This gene has 2 transcripts (splice variants), 245 orthologues, 7 paralogues and is associated with 1 phenotype. Broad expression in bone marrow (RPKM 14.8), stomach (RPKM 7.9) and 19 other tissues.

Summary

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]

PTGER2 Products (1)

mRNA Protein Name
NM_000956.4 NP_000947.2 prostaglandin E2 receptor EP2 subtype

PTGER2 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (62 - 314)

  • 0
  • 100
  • 200
  • 300
  • 358 a.a.
Protein Preferred Names Protein Names

prostaglandin E2 receptor EP2 subtype

  • PGE receptor EP2 subtype

PTGER2 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83597 Prostaglandin E Receptor EP2 Antibody (YA3342) WB, IHC-P, ICC/IF, FC Human, Mouse, Rat, Cow

Related Diseases

Diseases Alias
Asthma, Nasal Polyps, And Aspirin Intolerance

  • Asthma And Nasal Polyps

  • Asa Triad

  • Asthma, Aspirin-Induced, Susceptibility To

  • Asthma, Aspirin-Induced

  • Asthma, With Nasal Polyps And Aspirin Intolerance

  • ANPAI

  • Aia

  • Aspirin-Intolerant Asthma

  • Asthma Aspirin-Induced

  • Nasal Polyps Asthma And Aspirin Sensitivity

  • Samter Triad

  • Asthma With Aspirin Triad Including Nonsteroidal Anti-Inflammatory Activity And Nasal Polyps
Asthma

  • Chronic Obstructive Asthma

  • Asthma, Diminished Response To Antileukotriene Treatment In

  • Bronchial Hyperreactivity

  • Asthma, Susceptibility To

  • Asthma, Bronchial

  • Asthma, Protection Against

  • Asthma, Nocturnal, Susceptibility To

  • Nocturnal Asthma

  • Asthma-Related Traits

  • Asthma-Related Traits, Susceptibility To

  • Asthma, Nocturnal

  • Chronic Obstructive Asthma With Acute Exacerbation

  • Chronic Obstructive Asthma With Status Asthmaticus

  • Exercise Induced Asthma

  • Exercise-Induced Asthma

  • Bronchial Asthma

  • Asthma, Exercise-Induced

  • Idiosyncratic Asthma

  • Unspecified Asthma With Acute Exacerbation

  • Asthma, Unspecified, With Stated Status Asthmaticus

  • Status Asthmaticus Nos

  • Acute Severe Asthma

  • Acute Severe Bronchial Asthma

  • Status Asthma

  • Status Post Asthmaticus
Ocular Hypotension

  • Hypotony Of Eye
Iritis
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108560 (+)-Fluprostenol Activator / Unkown
HY-RS11376 PTGER2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-108560A 15(S)-Fluprostenol Activator / Unkown
HY-108560S (+)-Fluprostenol-d4 Activator / Unkown
HY-RS19072 Ptger2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25562 Ptger2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PTGER2 VGNC VGNC:33502
Macaca mulatta PTGER2 VGNC VGNC:76468
Mus musculus PTGER2 MGD MGI:97794
Rattus norvegicus PTGER2 RGD RGD:620020
Canis familiaris PTGER2 VGNC VGNC:45143
Others PTGER2 NCBI