Bcas3 - BCAS3 microtubule associated cell migration factor Gene
Also Known as K20D4; Phaf2; rudhira; 1500019F07Rik; 2610028P08Rik
Species: Mus musculus
Summary
Predicted to enable several functions, including acetyltransferase activator activity; beta-tubulin binding activity; and Histone Acetyltransferase binding activity. Involved in several processes, including negative regulation of focal adhesion assembly; positive regulation of cellular component organization; and regulation of GTPase activity. Located in cell leading edge; cell periphery; and Cytoskeleton. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; genitourinary system; hemolymphoid system; and yolk sac. Orthologous to human BCAS3 (BCAS3 microtubule associated cell migration factor). [provided by Alliance of Genome Resources, Apr 2022]
Bcas3 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001166642.1 | NP_001160114.1 | BCAS3 microtubule associated cell migration factor isoform b |
| NM_001166643.1 | NP_001160115.1 | BCAS3 microtubule associated cell migration factor isoform b |
| NM_138681.4 | NP_619622.3 | BCAS3 microtubule associated cell migration factor isoform a |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cell-cell signaling |
IMP
IMP: Inferred from mutant phenotype
|
22300583 | MGI |
| involved in positive regulation of endothelial cell migration |
IDA
IDA: Inferred from direct assay
|
22300583 | MGI |
| involved in regulation of actin cytoskeleton organization |
IDA
IDA: Inferred from direct assay
|
22300583 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cell leading edge |
IDA
IDA: Inferred from direct assay
|
22300583 | MGI |
| located in cell periphery |
IDA
IDA: Inferred from direct assay
|
16099728 | MGI |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
16099728 | MGI |
| located in cytoplasmic microtubule |
IDA
IDA: Inferred from direct assay
|
22300583 | MGI |
| located in intermediate filament cytoskeleton |
IDA
IDA: Inferred from direct assay
|
22300583 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
BCAS3 microtubule associated cell migration factor breast carcinoma-amplified sequence 3 homolog |
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