2. Gene
  3. Ptgis - prostaglandin I2 (prostacyclin) synthase Gene

Ptgis - prostaglandin I2 (prostacyclin) synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cyp8; Pgis; Cyp8a1

Gene ID: 19223 | Gene type: protein coding

About Ptgis

Summary

Predicted to enable heme binding activity and prostaglandin-I synthase activity. Acts upstream of or within decidualization and embryo implantation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; ear; early embryo; and genitourinary system. Human ortholog(s) of this gene implicated in essential hypertension and hypertension. Orthologous to human PTGIS (prostaglandin I2 synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptgis Products(1)

mRNA Protein Name
NM_008968.4 NP_032994.1 prostacyclin synthase precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within decidualization IDA
IDA: Inferred from direct assay
10385625 MGI
acts upstream of or within embryo implantation IDA
IDA: Inferred from direct assay
10385625 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10385625 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10385625 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostacyclin synthase

hydroperoxy icosatetraenoate dehydratase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11389 PTGIS Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptgis NCBI NCBI:5740