Plb1 - phospholipase B1 Gene

Rattus norvegicus

Also known as Phlpb

Gene ID: 192259 | Gene type: protein coding

About Plb1

Summary

Enables carboxylic ester hydrolase activity. Involved in glycerolipid catabolic process and retinol metabolic process. Located in brush border membrane. Orthologous to human PLB1 (Phospholipase B1). [provided by Alliance of Genome Resources, Apr 2022]

Plb1 Products(1)

mRNA	Protein	Name
NM_138898.2	NP_620253.1	phospholipase B1, membrane-associated precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables calcium-independent phospholipase A2 activity	IDA IDA: Inferred from direct assay	9442064	RGD
enables lysophospholipase activity	IDA IDA: Inferred from direct assay	1716922	RGD
enables phospholipase A2 activity	IDA IDA: Inferred from direct assay	1716922	RGD
enables retinyl-palmitate esterase activity	IDA IDA: Inferred from direct assay	8117729	RGD
enables triacylglycerol lipase activity	IDA IDA: Inferred from direct assay	9442064	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in diacylglycerol catabolic process	IDA IDA: Inferred from direct assay	9442064	RGD
involved in phosphatidylcholine catabolic process	IDA IDA: Inferred from direct assay	9442064	RGD
involved in phosphatidylethanolamine catabolic process	IDA IDA: Inferred from direct assay	9442064	RGD
involved in phosphatidylglycerol catabolic process	IDA IDA: Inferred from direct assay	9442064	RGD
involved in phospholipid metabolic process	IDA IDA: Inferred from direct assay	1716922	RGD
involved in retinol metabolic process	IDA IDA: Inferred from direct assay	8117729	RGD
involved in triglyceride catabolic process	IDA IDA: Inferred from direct assay	9442064	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in brush border membrane	IDA IDA: Inferred from direct assay	1716922	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

phospholipase B1, membrane-associated

PLB/LIP	lysophospholipase
phospholipase A2	phospholipase B
phospholipase B/lipase	triacylglycerol lipase

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10649	PLB1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Plb1	NCBI	NCBI:151056

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