2. Gene
  3. Pirt - phosphoinositide-interacting regulator of transient receptor potential channels Gene

Pirt - phosphoinositide-interacting regulator of transient receptor potential channels Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A530088H08Rik

Gene ID: 193003 | Gene type: protein coding

About Pirt

Summary

Enables phosphatidylinositol bisphosphate binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and transmembrane transporter binding activity. Acts upstream of or within several processes, including behavioral response to pain; phosphatidylinositol-mediated signaling; and positive regulation of cation channel activity. Located in plasma membrane. Is expressed in gut; nervous system; and olfactory epithelium. Orthologous to human PIRT (phosphoinositide interacting regulator of transient receptor potential channels). [provided by Alliance of Genome Resources, Apr 2022]

Pirt Products(1)

mRNA Protein Name
NM_178656.3 NP_848771.1 phosphoinositide-interacting protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables phosphatidylinositol bisphosphate binding IDA
IDA: Inferred from direct assay
18455988 MGI
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: Inferred from direct assay
18455988 MGI
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
18455988 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within behavioral response to pain IMP
IMP: Inferred from mutant phenotype
18455988 MGI
acts upstream of or within positive regulation of cation channel activity IMP
IMP: Inferred from mutant phenotype
18455988 MGI
acts upstream of or within response to heat IMP
IMP: Inferred from mutant phenotype
18455988 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
18455988 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphoinositide-interacting protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10572 PIRT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pirt NCBI NCBI:644139