Rab12 - RAB12, member RAS oncogene family Gene

Also Known as 2900054P15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19328

Summary

Predicted to enable GDP binding activity. Involved in cellular protein catabolic process; endosome to lysosome transport; and positive regulation of macroautophagy. Acts upstream of or within cellular response to interferon-gamma. Located in cytoplasmic vesicle and vacuole. Orthologous to human RAB12 (RAB12, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab12 Products (1)

mRNA Protein Name
NM_024448.3 NP_077768.3 ras-related protein Rab-12

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
19144319 MGI
involved in endosome to lysosome transport IMP
IMP: Inferred from mutant phenotype
21718402 MGI
involved in positive regulation of macroautophagy IMP
IMP: Inferred from mutant phenotype
23357852 MGI
involved in protein catabolic process IMP
IMP: Inferred from mutant phenotype
21718402 MGI
Cellular Component GO Annotation Evidence References Source
located in autophagosome IDA
IDA: Inferred from direct assay
23357852 MGI
located in lysosome IDA
IDA: Inferred from direct assay
21718402 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
19144319 MGI
located in recycling endosome membrane IDA
IDA: Inferred from direct assay
21718402 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-12

  • rab-13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11521 RAB12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180320 Lu AF58786 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab12 NCBI NCBI:201475