Rdh16 - retinol dehydrogenase 16 Gene

Also Known as CRAD; Rdh6; CRAD1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19683

Summary

Enables NAD-retinol dehydrogenase activity and identical protein binding activity. Involved in retinoid metabolic process and steroid metabolic process. Acts upstream of or within 9-cis-retinoic acid biosynthetic process. Located in endoplasmic reticulum lumen and endoplasmic reticulum membrane. Is integral component of organelle membrane. Is expressed in alimentary system; embryo; future spinal cord; liver; and salivary gland. Orthologous to human RDH16 (retinol dehydrogenase 16). [provided by Alliance of Genome Resources, Apr 2022]

Rdh16 Products (1)

mRNA Protein Name
NM_009040.3 NP_033066.1 retinol dehydrogenase 16
Molecular Function GO Annotation Evidence References Source
enables all-trans-retinol dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
9407098 MGI
enables identical protein binding IDA
IDA: Inferred from direct assay
16223484 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
16223484 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within 9-cis-retinoic acid biosynthetic process IDA
IDA: Inferred from direct assay
11876656 MGI
involved in retinoid metabolic process IDA
IDA: Inferred from direct assay
9407098 MGI
involved in steroid metabolic process IDA
IDA: Inferred from direct assay
9407098 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
16223484 MGI
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
15355969 MGI
located in organelle membrane IDA
IDA: Inferred from direct assay
16223484 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinol dehydrogenase 16

  • cis-retinol/androgen dehydrogenase 1

  • retinol dehydrogenase 6

  • retinol dehydrogenase type 6

Orthologs Information

Species Symbol Source ID
Homo sapiens Rdh16 NCBI NCBI:8608