RDH16 - retinol dehydrogenase 16 Gene

Also Known as RODH4; RODH-4; SDR9C8; hRDH-E

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8608

About RDH16

Cytogenetic location: 12q13.3 Genomic coordinates (GRCh38): 12:56,951,431-56,957,608 (from NCBI)

This gene has 2 transcripts (splice variants), 282 orthologues and 25 paralogues. Restricted expression toward liver (RPKM 111.9).

Summary

Enables NAD-retinol dehydrogenase activity; androstan-3-alpha,17-beta-diol dehydrogenase activity; and androsterone dehydrogenase activity. Involved in steroid metabolic process. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

RDH16 Products (2)

mRNA Protein Name
NM_001320108.2 NP_001307037.1 retinol dehydrogenase 16 isoform 2
NM_003708.5 NP_003699.3 retinol dehydrogenase 16 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables all-trans-retinol dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
9677409 GOA
enables androstan-3-alpha,17-beta-diol dehydrogenase activity IDA
IDA: Inferred from direct assay
9677409 GOA
enables androsterone dehydrogenase activity IDA
IDA: Inferred from direct assay
9677409 GOA
Biological Process GO Annotation Evidence References Source
involved in steroid metabolic process IDA
IDA: Inferred from direct assay
9677409 GOA
Cellular Component GO Annotation Evidence References Source
located in intracellular membrane-bounded organelle IDA
IDA: Inferred from direct assay
9677409 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RDH16 Protein Structure

adh_short

adh_short: short chain dehydrogenase (31 - 194)

  • 0
  • 100
  • 200
  • 300
  • 317 a.a.
Protein Preferred Names Protein Names

retinol dehydrogenase 16

  • human epidermal retinol dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11802 RDH16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RDH16 RGD RGD:735050
Canis familiaris RDH16 VGNC VGNC:52599
Others RDH16 NCBI