ELK4 - ETS transcription factor ELK4 Gene

Homo sapiens

Also known as SAP1

Gene ID: 2005 | Gene type: protein coding

About ELK4

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:205,607,943-205,632,011 (from NCBI)

This gene has 5 transcripts (splice variants), 200 orthologues, 28 paralogues and is associated with 48 phenotypes. Ubiquitous expression in prostate (RPKM 12.4), lymph node (RPKM 7.6) and 25 other tissues.

Summary

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

ELK4 Products(2)

mRNA	Protein	Name
NM_001973.4	NP_001964.2	ETS domain-containing protein Elk-4 isoform a
NM_021795.3	NP_068567.1	ETS domain-containing protein Elk-4 isoform b

ELK4 Protein Structure

Ets

0
100
200
300
400
431 a.a.

Protein Preferred Names

Protein Names

ETS domain-containing protein Elk-4

ELK4, ETS transcription factor

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04307	ELK4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ELK4	VGNC	VGNC:40305
Mus musculus	ELK4	MGD	MGI:102853
Felis catus	ELK4	VGNC	VGNC:61812
Macaca mulatta	ELK4	VGNC	VGNC:72211
Rattus norvegicus	ELK4	RGD	RGD:1310504
Bos taurus	ELK4	VGNC	VGNC:28434