2. Gene
  3. Sgca - sarcoglycan, alpha (dystrophin-associated glycoprotein) Gene

Sgca - sarcoglycan, alpha (dystrophin-associated glycoprotein) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Asg; 50DAG

Gene ID: 20391 | Gene type: protein coding

About Sgca

Summary

This gene encodes a member of the sarcoglycan alpha/epsilon family of transmembrane proteins. The encoded protein is part of the dystrophin-glycoprotein complex which links the extracellular matrix to the Cytoskeleton in muscle fibers. Disruption of this gene results in progressive muscular dystrophy and is associated with the development of embryonal rhabdomysarcoma. [provided by RefSeq, Dec 2012]

Sgca Products(1)

mRNA Protein Name
NM_009161.4 NP_033187.1 alpha-sarcoglycan precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
19531352 MGI
part of dystroglycan complex IDA
IDA: Inferred from direct assay
10678176 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
11259414 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10481911 MGI
part of sarcoglycan complex IDA
IDA: Inferred from direct assay
16524571 MGI
located in sarcolemma IDA
IDA: Inferred from direct assay
10481911 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-sarcoglycan

50 kDa dystrophin-associated glycoprotein

adhalin

alpha-SG

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12790 SGCA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgca NCBI NCBI:6442