2. Gene
  3. Sh3bp1 - SH3-domain binding protein 1 Gene

Sh3bp1 - SH3-domain binding protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 3BP-1

Gene ID: 20401 | Gene type: protein coding

About Sh3bp1

Summary

Enables GTPase activator activity and SH3 domain binding activity. Involved in positive regulation of GTPase activity and ruffle assembly. Located in bicellular tight junction. Orthologous to human SH3BP1 (SH3 domain binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sh3bp1 Products(3)

mRNA Protein Name
NM_001316684.2 NP_001303613.1 SH3 domain-binding protein 1 isoform 1
NM_001316685.2 NP_001303614.1 SH3 domain-binding protein 1 isoform 3
NM_009164.4 NP_033190.2 SH3 domain-binding protein 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
7621827 MGI
enables SH3 domain binding IPI
IPI: Inferred from physical interaction
8438166 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of GTPase activity IDA
IDA: Inferred from direct assay
7621827 MGI
involved in ruffle assembly IMP
IMP: Inferred from mutant phenotype
7621827 MGI
Cellular Component GO Annotation Evidence Reference Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
22891260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH3 domain-binding protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12829 SH3BGRL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12830 SH3BP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sh3bp1 NCBI NCBI:23616