2. Gene
  3. Itsn2 - intersectin 2 Gene

Itsn2 - intersectin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ese2; Sh3d1B; Sh3p18; mKIAA1256

Gene ID: 20403 | Gene type: protein coding

About Itsn2

Summary

Predicted to enable molecular adaptor activity. Predicted to be involved in clathrin-dependent synaptic vesicle endocytosis and positive regulation of dendrite extension. Predicted to act upstream of or within cell differentiation. Predicted to be located in centrosome. Predicted to be active in several cellular components, including clathrin-coated pit; intracellular vesicle; and presynaptic membrane. Is expressed in several structures, including endocrine gland; ileum; male reproductive gland or organ; nervous system; and thymus. Used to study nephrotic syndrome. Orthologous to human ITSN2 (intersectin 2). [provided by Alliance of Genome Resources, Apr 2022]

Itsn2 Products(3)

mRNA Protein Name
NM_001198968.2 NP_001185897.1 intersectin-2 isoform 1
NM_001198969.2 NP_001185898.1 intersectin-2 isoform 3
NM_011365.4 NP_035495.2 intersectin-2 isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19064729 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

intersectin-2

EH and SH3 domains protein 2

EH domain and SH3 domain regulator of endocytosis 2

Eh domain, SH3 domain regulator of endocytosis 2

SH3 domain protein 1B

SH3 domain-containing protein 1B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06998 ITSN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itsn2 NCBI NCBI:50618