2. Gene
  3. Pmel - premelanosome protein Gene

Pmel - premelanosome protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Si; Silv; gp87; gp100; Pmel17; D12S53Eh; D10H12S53E

Gene ID: 20431 | Gene type: protein coding

About Pmel

Summary

Predicted to enable identical protein binding activity. Involved in positive regulation of melanin biosynthetic process. Acts upstream of or within melanin biosynthetic process. Located in melanosome. Is expressed in several structures, including alimentary system; genitourinary system; mesenchyme derived from neural crest; nervous system; and sensory organ. Orthologous to human PMEL (premelanosome protein). [provided by Alliance of Genome Resources, Apr 2022]

Pmel Products(1)

mRNA Protein Name
NM_021882.5 NP_068682.2 melanocyte protein PMEL precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within melanin biosynthetic process IMP
IMP: Inferred from mutant phenotype
7665913 MGI
involved in positive regulation of melanin biosynthetic process IMP
IMP: Inferred from mutant phenotype
21949658 MGI
Cellular Component GO Annotation Evidence Reference Source
located in melanosome IDA
IDA: Inferred from direct assay
11266470 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

melanocyte protein PMEL

melanocyte protein pmel 17

silver locus protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124857 7DG Inhibitor 98% Unkown
HY-RS10760 PMEL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmel NCBI NCBI:6490