St8sia4 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 Gene

Also Known as PST; PST-1; Siat8d; SIAT8-D; ST8SiaIV

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20452

Summary

Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Predicted to be involved in ganglioside biosynthetic process; glycoprotein metabolic process; and oligosaccharide metabolic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and lung. Orthologous to human ST8SIA4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]

St8sia4 Products (2)

mRNA Protein Name
NM_001159745.2 NP_001153217.1 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase isoform 2 precursor
NM_009183.3 NP_033209.1 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IDA
IDA: Inferred from direct assay
8690732 MGI
Biological Process GO Annotation Evidence References Source
involved in sialylation IDA
IDA: Inferred from direct assay
8690732 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

  • alpha-2,8-sialyltransferase 8D

  • polysialyltransferase-1

  • sialyltransferase 8 (alpha-2, 8-sialyltransferase) D

  • sialyltransferase 8D

  • sialyltransferase St8Sia IV

  • sialytransferase St8Sia IV

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70301 ST8 alpha-2,8-Sialyltransferase 4 / Unkown
HY-RS13858 ST8SIA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens St8sia4 NCBI NCBI:7903