Slc22a2 - solute carrier family 22 (organic cation transporter), member 2 Gene

Also Known as Oct2; Orct2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20518

Summary

Enables several functions, including pyrimidine nucleoside transmembrane transporter activity; toxin transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in toxin transport and xenobiotic transport. Acts upstream of or within cation transport. Located in apical plasma membrane. Is expressed in several structures, including metanephros; nasal cavity mucosa; nervous system; placenta; and ureter. Human ortholog(s) of this gene implicated in acute kidney failure. Orthologous to human SLC22A2 (solute carrier family 22 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a2 Products (2)

mRNA Protein Name
NM_001355767.1 NP_001342696.1 solute carrier family 22 member 2 isoform 2
NM_013667.3 NP_038695.1 solute carrier family 22 member 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables organic cation transmembrane transporter activity IDA
IDA: Inferred from direct assay
12176030 MGI
enables pyrimidine nucleoside transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
20477935 MGI
enables toxin transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
20477935 MGI
enables xenobiotic transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
20477935 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular detoxification IMP
IMP: Inferred from mutant phenotype
20477935 MGI
acts upstream of or within monoatomic cation transport IDA
IDA: Inferred from direct assay
12176030 MGI
involved in xenobiotic transport IMP
IMP: Inferred from mutant phenotype
20477935 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
20477935 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 22 member 2

  • organic cation transporter 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13072 SLC22A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc22a2 NCBI NCBI:6582