Slc31a2 - solute carrier family 31, member 2 Gene

Mus musculus

Also known as CTR2

Gene ID: 20530 | Gene type: protein coding

About Slc31a2

Summary

Acts upstream of or within cellular copper ion homeostasis and regulation of copper ion transmembrane transport. Located in late endosome; membrane; and recycling endosome. Is expressed in brain; retina nuclear layer; and urinary system. Orthologous to human SLC31A2 (solute carrier family 31 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc31a2 Products(2)

mRNA	Protein	Name
NM_001290518.1	NP_001277447.1	probable low affinity copper uptake protein 2 isoform 2
NM_025286.3	NP_079562.1	probable low affinity copper uptake protein 2 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
NOT enables copper ion transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	24167251	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	24167251	MGI

Biological Process GO Annotation	Evidence	Reference	Source
NOT acts upstream of or within copper ion transmembrane transport	IMP IMP: Inferred from mutant phenotype	24167251	MGI
NOT acts upstream of or within copper ion transport	IMP IMP: Inferred from mutant phenotype	24167251	MGI
acts upstream of or within intracellular copper ion homeostasis	IGI IGI: Inferred from genetic interaction	24167251	MGI
acts upstream of or within intracellular copper ion homeostasis	IMP IMP: Inferred from mutant phenotype	24167251	MGI
acts upstream of or within regulation of copper ion transmembrane transport	IMP IMP: Inferred from mutant phenotype	24167251	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in late endosome	IDA IDA: Inferred from direct assay	24167251	MGI
located in membrane	IDA IDA: Inferred from direct assay	24167251	MGI
located in recycling endosome	IDA IDA: Inferred from direct assay	24167251	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

probable low affinity copper uptake protein 2

copper transporter 2

solute carrier family 31 (copper transporters), member 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13189	SLC31A2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc31a2	NCBI	NCBI:1318

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