SLC31A2 - solute carrier family 31 member 2 Gene

Also Known as CTR2; COPT2; hCTR2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1318

About SLC31A2

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:113,151,007-113,164,140 (from NCBI)

This gene has 3 transcripts (splice variants), 223 orthologues and 1 paralogue. Broad expression in salivary gland (RPKM 28.8), spleen (RPKM 6.8) and 18 other tissues.

Summary

Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in cellular copper ion homeostasis. Predicted to act upstream of or within regulation of copper ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC31A2 Products (1)

mRNA Protein Name
NM_001860.3 NP_001851.1 probable low affinity copper uptake protein 2

SLC31A2 Protein Structure

Ctr

Ctr: Ctr copper transporter family (1 - 135)

  • 0
  • 100
  • 143 a.a.
Protein Preferred Names Protein Names

probable low affinity copper uptake protein 2

  • copper transporter 2

SLC31A2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLC31A2 O15432 BNIP3 Homo sapiens Q12983
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Menkes Disease

  • Copper Transport Disease

  • Menkes Syndrome

  • MNK

  • Kinky Hair Disease

  • Steely Hair Disease

  • Menkes Kinky-Hair Syndrome

  • Mk

  • Steely Hair Syndrome

  • Menkea Syndrome

  • Md

  • Menkes Kinky Hair Syndrome

  • Hypocupremia, Congenital

  • Kinky Hair Syndrome

  • X-Linked Copper Deficiency

  • Menkes Kinky Hair Disease
Deficiency Anemia

  • Anemia

  • Deficiency Anemias

  • Anaemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13189 SLC31A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC31A2 VGNC VGNC:77456
Canis familiaris SLC31A2 VGNC VGNC:46355
Mus musculus SLC31A2 MGD MGI:1333844
Bos taurus SLC31A2 VGNC VGNC:34814
Rattus norvegicus SLC31A2 RGD RGD:1307963
Felis catus SLC31A2 VGNC VGNC:102982
Others SLC31A2 NCBI